Case 1 - Initiating ARV Therapy

Title:

Case 1 - Initiating ARV Therapy

Topic: Infectious Diseases
Relevant Terms: HIV, HIV treatment regimens
Primary Audience: Infectious disease specialists, HIV treaters, and other health care professionals involved in the treatment of patients with HIV.
Launch Date: 31-Mar-16
Credits: AMA PRA Category 1 Credit
Expiration Date: The accreditation for this activity has expired.
Curriculum Name: Challenging Cases in HIV Management: The Patient Waiting Room

Learning Objectives

After completing this activity, the participant will demonstrate the ability to:

  1. Utilize evidence-based guidelines as well as clinical knowledge of available and emerging therapies to develop initial HIV treatment regimens based on individual patient characteristics.
  2. Review the cost-effectiveness of available HIV therapies.
  3. Develop simplified HIV treatment regimens that reflect patient preference and increase adherence.
  4. Differentiate available and emerging HIV treatment regimens based on resistance profile.
  5. Apply knowledge of effective switch strategies and NRTI-sparing regimens that have demonstrated a low risk of virological failure in patients who would benefit from treatment alteration.

    Faculty

    Paul E. Sax, MD
    Clinical Director
    Division of Infectious Diseases
    Brigham and Women's Hospital Professor of Medicine
    Harvard Medical School
    Boston, MA
    Richard A. Elion, MD
    Associate Clinical Professor of Medicine
    George Washington University School of Medicine
    Washington, DC
    Charles Hicks, MD
    Professor of Medicine
    Director
    Owen Clinic
    University of California
    San Diego, CA
    Provider Statement:
    This continuing medical education activity is provided by 
    Educational Partner:
     

    Support Statement:
    This activity is supported by an educational grant from ViiV Healthcare.

    Activity Chair:
    Paul E. Sax, MD
    Clinical Director
    Division of Infectious Diseases
    Brigham and Women's Hospital Professor of Medicine
    Harvard Medical School
    Boston, MA

    Disclosures:
    Advisory Board: AbbVie, Bristol-Myers Squibb, GlaxoSmithKline/ViiV, Gilead, Janssen, Merck
    Investigator: Bristol-Myers Squibb, GlaxoSmithKline/ViiV, Gilead, Merck
     
    Faculty:
    Richard A. Elion, MD
    Associate Clinical Professor of Medicine
    George Washington University School of Medicine
    Washington, DC
     
    Disclosures:
    Consultant: Gilead, Janssen, ViiV
    Speakers Bureau: Bristol-Myers Squibb, Gilead, Janssen, Merck, ViiV
    Contracted Research: AbbVie, Bristol-Myers Squibb, Gilead, Janssen, Merck, ViiV
     
    Charles Hicks, MD
    Professor of Medicine
    Director
    Owen Clinic
    University of California
    San Diego, CA
     
    Disclosures:
    Advisory Board: Bristol-Myers Squibb, Gilead, Merck, Janssen, ViiV
    Contributor: UpToDate
     
    External Reviewer:
    Rebecca A. Clark, MD
    No relevant financial relationships to disclose.
     
    National Jewish Health and Vindico Medical Education staff report the following relationship(s):
    No relevant financial relationships to disclose.

    Signed disclosures are on file at National Jewish Health, Office of Professional Education, and Vindico Medical Education, Office of Medical Affairs and Compliance.
     
    Disclosures:
    In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all planners, teachers, authors, and reviewers involved in the development of CME content are required to disclose to the accredited provider their relevant financial relationships. Relevant financial relationships will be disclosed to the activity audience prior to viewing content.
     
    Accreditation:
    National Jewish Health is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 

    Credit Designation:
    National Jewish Health designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    This enduring material is approved from the date of original release, March 31, 2016 through June 30, 2017.

    How to Participate in this Activity and Obtain CME Credit:
    To participate in this CME activity, you must reference the objectives, answer the pretest questions, watch, read, and listen to the content, complete the CME posttest, and then fill in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 66% of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, National Jewish Health will issue an AMA PRA Category 1 Credits™ Certificate.

    Overview: With the rapid advances in HIV management, health care providers need to remain informed about guideline changes, developments in antiretroviral therapy, and special issues for patients with concurrent infections. This interactive, case-based CME activity will review evidence-based guidelines for initiating antiretroviral therapy in patients who also require treatment/prevention of opportunistic infections. Expert commentaries offered by faculty will discuss ways to optimize treatment strategies that incorporate clinical research and guidelines into practice.

    Target Audience: The intended audience for the activity is infectious disease specialists, HIV treaters, and other health care professionals involved in the treatment of patients with HIV.

    Learning Objectives:
    Upon successful completion of the educational series, participants should be better able to:
    • Utilize evidence-based guidelines as well as clinical knowledge of available and emerging therapies to develop initial HIV treatment regimens based on individual patient characteristics.
    • Review the cost-effectiveness of available HIV therapies.
    • Develop simplified HIV treatment regimens that reflect patient preference and increase adherence.
    • Differentiate available and emerging HIV treatment regimens based on resistance profile.
    • Apply knowledge of effective switch strategies and NRTI-sparing regimens that have demonstrated a low risk of virological failure in patients who would benefit from treatment alteration.
    Unlabeled and Investigational Usage:
    The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.

    Copyright Statement:
    Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2016 Vindico Medical Education. All rights reserved.

    No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of National Jewish Health and Vindico Medical Education continuing education activities does not necessarily reflect the views and opinions of National Jewish Health and Vindico Medical Education. Neither National Jewish Health, nor Vindico Medical Education, nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

    CME Questions?
    Contact us at:
    National Jewish Health: proed@njhealth.org or 303-398-1000.
    Vindico Medical Education: cme@vindicocme.com or 856-994-9400, ext. 504.
     
     
    COURSE VIEWING REQUIREMENTS
    Supported Browsers:
    Internet Explorer 9.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1
    Google Chrome 28.0+ for Windows, Mac OS, or Linux
    Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
    Safari 6.0+ for Mac OSX 10.7 and above
    Supported Phones & Tablets:
    Android 4.0.3 and above
    iPhone/iPad with iOS 6.1 or above