Case 2 - Managing HIV Therapy in Patients with Comorbidities

Title:

Case 2 - Managing HIV Therapy in Patients with Comorbidities

Topic: Infectious Diseases
Relevant Terms: HIV, HIV treatment regimens
Primary Audience: Infectious disease specialists, HIV treaters, and other health care professionals involved in the treatment of patients with HIV.
Launch Date: 31-Mar-16
Credits: 0.75 AMA PRA Category 1 Credit
Expiration Date: The accreditation for this activity has expired.
Curriculum Name: Challenging Cases in HIV Management: The Patient Waiting Room

Learning Objectives

After completing this activity, the participant will demonstrate the ability to:

  1. Utilize evidence-based guidelines as well as clinical knowledge of available and emerging therapies to develop initial HIV treatment regimens based on individual patient characteristics.
  2. Review the cost-effectiveness of available HIV therapies.
  3. Develop simplified HIV treatment regimens that reflect patient preference and increase adherence.
  4. Differentiate available and emerging HIV treatment regimens based on resistance profile.
  5. Apply knowledge of effective switch strategies and NRTI-sparing regimens that have demonstrated a low risk of virological failure in patients who would benefit from treatment alteration.

    Faculty

    Paul E. Sax, MD
    Clinical Director
    Division of Infectious Diseases
    Brigham and Women's Hospital Professor of Medicine
    Harvard Medical School
    Boston, MA
    Grace A. McComsey, MD
    Professor of Medicine and Pediatrics
    Division Chief
    Pediatric Infectious Diseases and Rheumatology
    Case Western Reserve University
    Cleveland Clinic
    Cleveland, OH
    Edgar T. Overton, MD
    Associate Professor of Medicine
    Medical Director
    UAB 1917 HIV Clinic
    Birmingham, AL
    Provider Statement:
    This continuing medical education activity is provided by
    Educational Partner:
     
     
    Support Statement:
    This activity is supported by an educational grant from ViiV Healthcare.
     
    Activity Chair:
    Paul E. Sax, MD
    Clinical Director
    Division of Infectious Diseases
    Brigham and Women's Hospital Professor of Medicine
    Harvard Medical School
    Boston, MA     
     
    Disclosures:
    Advisory Board: AbbVie, Bristol-Myers Squibb, GlaxoSmithKline/ViiV, Gilead, Janssen, Merck
    Investigator: Bristol-Myers Squibb, GlaxoSmithKline/ViiV, Gilead, Merck
     
    Faculty:
    Grace A. McComsey, MD
    Professor of Medicine and Pediatrics
    Division Chief
    Pediatric Infectious Diseases and Rheumatology
    Case Western Reserve University
    Cleveland Clinic
    Cleveland, OH
     
    Disclosures:
    Advisory Board: Bristol-Myers Squibb, Gilead, ViiV
    Consultant: Bristol-Myers Squibb, Gilead, ViiV
    Investigator: AstraZeneca, Bristol-Myers Squibb, Gilead, ViiV
     
    Edgar T. Overton, MD
    Associate Professor of Medicine
    Medical Director
    UAB 1917 HIV Clinic
    Birmingham, AL
     
    Disclosures:
    Contracted Research (paid to institution): Bristol-Myers Squibb, Gilead, Janssen
     
    External Reviewer:
    Rebecca A. Clark, MD
    No relevant financial relationships to disclose.
     
    National Jewish Health and Vindico Medical Education staff report the following relationship(s):
    No relevant financial relationships to disclose.
     
    Signed disclosures are on file at National Jewish Health, Office of Professional Education, and Vindico Medical Education, Office of Medical Affairs and Compliance.
     
    Disclosures:
    In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all planners, teachers, authors, and reviewers involved in the development of CME content are required to disclose to the accredited provider their relevant financial relationships. Relevant financial relationships will be disclosed to the activity audience prior to viewing content.
     
    Accreditation:
    National Jewish Health is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 
     
    Credit Designation:
    National Jewish Health designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
     
    This enduring material is approved from the date of original release, March 31, 2016 through June 30, 2017.
     
    How to Participate in this Activity and Obtain CME Credit:
    To participate in this CME activity, you must reference the objectives, answer the pretest questions, watch, read, and listen to the content, complete the CME posttest, and then fill in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 66% of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, National Jewish Health will issue an AMA PRA Category 1 Credits™ Certificate.
     
    Overview: People living with HIV are often affected by multiple chronic diseases that pose complex challenges for providers, especially regarding drug management. In this interactive, case-based activity, a variety of topics pertaining to the treatment of patients with HIV and other comorbidities will be reviewed. Expert commentaries offered by faculty will cover key issues, such as selecting appropriate HIV treatment given specific comorbidities, assessing for potential drug interactions, and developing strategies to maximize safety.
     
    Target Audience: The intended audience for the activity is infectious disease specialists, HIV treaters, and other health care professionals involved in the treatment of patients with HIV.
     
    Learning Objectives:
    Upon successful completion of the educational series, participants should be better able to:
    • Utilize evidence-based guidelines as well as clinical knowledge of available and emerging therapies to develop initial HIV treatment regimens based on individual patient characteristics.
    • Review the cost-effectiveness of available HIV therapies.
    • Develop simplified HIV treatment regimens that reflect patient preference and increase adherence.
    • Differentiate available and emerging HIV treatment regimens based on resistance profile.
    • Apply knowledge of effective switch strategies and NRTI-sparing regimens that have demonstrated a low risk of virological failure in patients who would benefit from treatment alteration.
    Unlabeled and Investigational Usage:
    The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.
     
    Copyright Statement:
    Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2016 Vindico Medical Education. All rights reserved.
     
    No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of National Jewish Health and Vindico Medical Education continuing education activities does not necessarily reflect the views and opinions of National Jewish Health and Vindico Medical Education. Neither National Jewish Health, nor Vindico Medical Education, nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.
     
    CME Questions?
    Contact us at:
    National Jewish Health: proed@njhealth.org or 303-398-1000.
    Vindico Medical Education: cme@vindicocme.com or 856-994-9400, ext. 504.
     
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